
蒋莱博士致力于纳米自组装、纳米乳化、抗生素递送、分子影像学的交叉学科研究。目前以第一作者(含共同)身份在Journal of controlled Release、ACS infectious Diseases、RSC advances等国外知名学术期刊发表论文6篇。
教育与工作背景:
2021年3月- 2023年7月 厦门大学公共卫生学院博士后,合作导师:刘刚教授。
2019年3月- 2021年1月 新加坡南洋理工大学材料科学与工程专业博士后,合作导师:Joachim Say Cyhe Loo。
20015年6月-2019年7月 英国女王大学 Queen’s University Belfast实验医学专业,获博士学位,导师:Christopher J. Scott。
2012年9月-2015年3月 天津理工大学化学化工学院药物化学专业,获硕士学位,导师:王亮教授。
代表性成果:
Lai Jiang, Michelle K. Greene, Jose Luis Insua, Joana Sa Pessoa, Donna M. Small, Peter Smyth, Aidan P. McCann, Francesco Cogo, José A. Bengoechea, Clifford C. Taggart, Christopher J. Scott *. Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles. Journal of Controlled Release. 2018, 279: 316-325.
Lai Jiang, Jia Lin, Clifford C. Taggart, José A. Bengoechea and Christopher J. Scott *. Nanodelivery strategies for the treatment of multidrug-resistant bacterial infections. Journal of Interdisciplinary Nanomedicine. 2018, 3: 111-121.
Aidan P. McCann, Peter Smyth, Francesco Cogo, William J. McDaid, Lai Jiang, Jia Lin, Emma Evergren, Roberta E. Burden, Sandra Van Schaeybroeck, Christopher J. Scott & James F. Burrows *. USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells. Cell Communication and Signaling. 2018, 16: 77.
Lai Jiang #, Hiang Wee Lee # and Say Chye Joachim Loo *. Therapeutic lipid-coated hybrid nanoparticles against bacterial infections. RSC Advances. 2020, 10: 8497-8517.
Lai Jiang and Say Chye Joachim Loo *. Intelligent Nanoparticle-Based Dressings for Bacterial Wound Infections. ACS Applied Bio Materials. Special Issue: Functional Biomaterials for Infectious Diseases, 2021, 4(5):14.
Chuan Hao Tan #, Lai Jiang #, Wenrui Li #, Siew Herng Chan, Jong-Suep Baek, Noele Kai Jing Ng, Talgat Sailov, Sharad Kharel, Kelvin Kian Long Chong, and Say Chye Joachim Loo *. Lipid-Polymer Hybrid Nanoparticles Enhance the Potency of Ampicillin against Enterococcus faecalis in a Protozoa Infection Model. ACS Infectious Diseases, 2021, 7(6):1607-1618.